Table 5.

Top CDR3 sequences in Rasmussen encephalitis brain specimens from the study cohort.

Case ID	CDR3 (amino acid)	CDR3 length (nt)	Brain (%)	TRBV gene	Blood (%)	TRBV gene
RECP32	CASSQDEGDEQYF	39	9.22	3	0	n.a.
	CASSLNPDRGIYEQFF	48	5.01	7	0	n.a.
RECP33	CAISESNYGYTF	36	22.26	6,10	0.13	6,10
	CASSLLVVESELHTGELFF	57	13.47	4,5	0.004	5
	CASSDSRGNIQYF	39	6.08	6	0	n.a.
	CASSKTSGPDNEQFF	45	5.40	7,11	0.004	7
RECP34	CASAEEWSSYNSPLHF	48	6.65	6,10	0	n.a.
	CASTLLRDTDTQYF	42	4.89	2	0.027	2
	CASSQDTPGQFYEQYF	48	4.62	1,4,5,7,13	0	n.a.
RECP35	CASSLRGTGNTEAFF	45	8.07	2,4,7,12,19,27,28,30	0	n.a.
	CASGPGGPSTGELFF	45	7.18	12,13	0.003	13
	CASSTSSTDTQYF	39	5.15	2,6	0	n.a.
RECP37	CASSQDPQGALNEQFF	48	17.13	4,5,7,11	0.009	4
	CASSYRPESYNEQFF	45	6.83	6	0.044	6
	CASGRGTSGPTGELFF	48	4.95	12	0.003	12
RECP40	CASSVAYEQYF	33	12.31	2,3,6,10,12,25,27	0.006	6
	CASAVAYEQYF	33	9.85	3,6,10,12,27	0	n.a.
RECP42	CASSVDHRAGKPYEQYF	51	47.03	5,19	0.008	19
	CATSVTTGGYTEAFF	45	9.61	12,24	0.059	24
	CASSGGSTDTQYF	39	8.75	4,19	0.004	19
RECP43	CASSTPGQGIGGYTF	45	15.44	19	0	n.a.
	CASSLQDRGPGGEQYV	48	5.65	7,11	0	n.a.
RECP45	CASSLRNYDDRVGYYEQYF	57	13.38	6,12,27,28	0.003	27
	CASSLGTGDRSNQPQHF	51	6.94	6,28	0.009	28
RECP46	CASTLQMNTEAFF	39	5.62	6	0.005	6
RECP47	CASGYEGGSTEAFF	42	9.60	12	15.09	7,12
RECP48	CASSSDGNTGELFF	42	7.49	5	0	n.a.
RECP49	CASQLGAATGYTF	39	70.02	4,5,7,11	3.8	3,4,5,6,7,11
RECP50	CASSPDRVETQYF	39	12.15	7	0	n.a.
	CVSSPGVPFTRFNTEAFF	54	8.40	12	0	n.a.
	CASSLSSFQETQYF	42	5.14	7,11	0	n.a.

CDR3, third complementarity region; RECP, Rasmussen Encephalitis Children’s Project; n.a., not applicable.