Figure 3.

Frequency of ocular health scores—data at BL and 1 year post-MSC transplantation. Ocular discharge, hyperemia, corneal opacity, and vascularization were graded as absent (0), mild (1), moderate (2), or severe (3). The data presented correspond to 11 animals that at BL were classified with mild–moderate KCS and 1 animal with severe KCS. The Wilcoxon matched pairs test was used to compare scores at BL and after treatment with MSCs; **p < 0.01. Although lower grade frequency increased overall with treatment and there were no regression or worsening, statistically significant improvements were only observed regarding ocular discharge and hyperemia. There was not enough statistical power to test improvements in corneal opacity and vascularization, though results show a trend toward improvement. @Insufficient data for statistical evaluation. BL, baseline; MSC, mesenchymal stem cell.