Table 1.
Mitochondrial indicators, including (1) total area of mitochondria, (2) cellular area, (3) mitochondrial content, (4) mitochondrial perimeter, (5) mitochondrial circularity, (6) average perimeter, (7) average mitochondrial area, (8) average circularity, (9) area/perimeter, (10) area/perimeter normalized to minor axis, (11) minor axis, (12) area/perimeter normalized to circularity, were calculated using ARPE-19 cells under oxidative stress.
Mitochondrial Morphology Changes under Oxidative Stress
| Mitochondrial Morphology | Control | Oxidative Stress (t = 60 min) |
|---|---|---|
| Total Area Mitochondria | 1.60 | 0.53 |
| Cellular Area | 9.9 | 9.9 |
| Mitochondrial Content | 16 | 5.3 |
| Mitochondrial Perimeter | 40 | 25 |
| Mitochondrial Circularity | 13 | 5.8 |
| Average Perimeter | 0.98 | 1.2 |
| Average Area | 0.039 | 0.025 |
| Average Circularity | 0.33 | 0.28 |
| Area/Perimeter | 0.040 | 0.021 |
| Area/Perimeter normalized to minor axis | 0.49 | 0.28 |
| Minor Axis | 0.082 | 0.076 |
| Area/Perimeter Normalized to Circularity | 0.12 | 0.076 |