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. 2016 Dec 15;25(24):1853–1862. doi: 10.1089/scd.2016.0212

FIG. 6.

FIG. 6.

Comparison between twin and control SBM miRNA expression profile. (A) Thirty-seven miRNAs (orange) were found solely in SBM from control blastocysts and are all coexpressed from TE cells; 22 miRNAs (olive) were found in SBMs from both control and twin blastocysts and are all coexpressed from TE cells; 26 miRNAs (blue) were found exclusively in SBM from twin blastocysts, but only 53.8% (14/26, blue, framed) are coexpressed from TE cells. (B) The volcano plot shows nine miRNAs significantly less abundant in SBM from twins versus control reproductively competent blastocysts, with a FC variable between −167.6 and −2.8, and six miRNAs instead significantly more abundant, with a FC between 2.7 and 319,148. Interestingly, miR-30c, putative biomarker of reproductive potential, was found in the former cluster with a FC −47.0.