Skip to main content
. 2016 Nov 23;13(12):955–962. doi: 10.7150/ijms.17290

Figure 3.

Figure 3

the blockade effect of exendin(9-39) in the IT group. a. the POMC neurons in the hypothalamic tissue at 100× magnification. The arrow indicates a POMC neuron stained by the immunohistochemistry stain. b, the amount of POMC derivative in the pituitary quantified by Western blot. Some IT rats (IT-b rats), S-IT rats (S-IT-b rats) and control rats (control-b rats) were given GLP-1 antagonist before sacrifice. The relative content level of POMC-derived peptides of the IT-b rats was significantly lower than that of the IT rats. The asterisk means significantly different compared to the S-IT group (P < 0.05); control-b, control group rats accepted GLP-1 receptor blockade; GLP-1, glucagon-like peptide 1; IT, ileal transposition; IT-b, ileal transposition rats accepted GLP-1 receptor blockade; POMC, pro-opiomelanocortin; S-IT, sham ileal transposition; S-IT-b, sham ileal transposition accepted GLP-1 receptor blockade.