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BrdUrd labeling of cells in DG-SGZ of 3-month-old (A and B) and 1-year-old (C and D) WT and PDGF-APPSw,Ind transgenic (Tg) mice. BrdUrd-labeled cells appear as black dots in A and C. The significance of differences between the number of BrdUrd-immunopositive cells in WT and transgenic mice in B and D was determined by Student's t test (n = 3-4).
