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Cyclin T1 preferentially represses genes for mitochondrial function. Ventricular transcript levels were determined by real-time QRT–PCR, and normalized to GAPDH. Results shown are mean changes in gene expression in the hypertrophied hearts of cyclin T1 and Gq transgenic mice, relative to nontransgenic littermates (N=5). Induction (⩾1.5) and repression (⩽0.75) are highlighted in red and blue, respectively.
