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. Author manuscript; available in PMC: 2017 Jul 13.
Published in final edited form as: Cell Host Microbe. 2016 May 27;20(1):83–90. doi: 10.1016/j.chom.2016.05.015

Figure 4. ZIKV Infection Induces an Antiviral Response in HCs.

Figure 4

HCs from five donors were infected with ZIKV (PR 2015) at an MOI of 1, and antiviral gene expression determined by qRT-PCR. Gene expression data are represented as fold change relative to time-matched, mock-infected controls (gene expression normalized to GAPDH − ΔΔCT method). Individual donors are depicted as separate bars, organized from donor 1 to donor 5, within each time point block. Viral titers determined in Figure 1 are represented as a separate heat map below each group of genes. (A) shows type I IFNs, (B) shows RIG-I-like receptors, and (C) shows antiviral effector genes. hpi, hours post-infection.