Figure 4.

Representative photomicrographs showing the difference in the number/distribution of CD3 positive cells in spleen, thymus and lung, between BTV-infected and Mock mice. IHC against CD3, 100X. A significant decrease in the number of CD3+ cells was observed in spleen and thymus from infected animals. Populations of CD3+ cell were restricted to periarteriolar areas in spleen (asterisk). A mild increase in the number of CD3+ cells, dispersed throughout the pulmonary parenchyma, was also observed.