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. 2016 Nov 24;12(12):1448–1460. doi: 10.7150/ijbs.14967

Figure 6.

Figure 6

Representative micrographs of immunohistochemical technique against MAC387 antibody in spleen, thymus and lungs from BTV-4-infected and Mock animals. IHC against MAC387 antibody, 100X. Positivity against MAC387 antibody in Mock-infected mice was mainly found in medullar sinuses (arrow), whereas in infected individuals the number of MAC387+ cells was increased, being scattered throughout the white pulp (asterisk). Immunoreactivity against MAC387 antibody was higher in the thymus from BTV-4-infected mice when compared with control animals, mainly in peripheral areas of the thymic parenchyma. Few small foci of MAC387+ cells (arrow) present in lung of BTV-infected animal, close to a bronchiole.