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Effect of NPM1mA on the expression of Bax in THP-1 cells after drug treatment. (A, B) THP-1 cells expressing NPM1mA or pEGFPC1 were treated with DNR (0.25 μM, 24h). (C, D) THP-1 cells expressing NPM1mA or pEGFPC1 were treated with Ara-C (8.5 μM, 24h). Quantitative RT-PCR and Western blot were used to assay the expression of Bax. Asterisks (*) indicate significant differences in relation to Blank or pEGFPC1 group cells.
