Table 1.
Correlation of Rab14 expression and the clinicopathological characteristics in invasive BC (n=130).
| Characteristics | n | Rab14 expression High expression, n (%) Low expression, n (%) |
P value | |
|---|---|---|---|---|
| Age (years) | 0.574 | |||
| <45 | 15 | 7 (47) | 8 (53) | |
| 45-55 | 61 | 37 (61) | 24 (39) | |
| >55 | 54 | 33 (61) | 21 (39) | |
| Tumor size (cm) | 0.034 | |||
| ≤2.5 | 79 | 41 (52) | 38 (48) | |
| >2.5 | 51 | 36 (71) | 15 (29) | |
| Lymph node metastasis | <0.001 | |||
| 0 | 71 | 30 (42) | 41 (58) | |
| 1-2 | 32 | 24 (75) | 8 (25) | |
| >2 | 27 | 23 (85) | 4 (15) | |
| Distant metastasis | 0.001 | |||
| Yes | 118 | 65 (55) | 53 (45) | |
| No | 12 | 12 (100) | 0 (0) | |
| Histological grade | 0.035 | |||
| well (І) | 14 | 5 (36) | 9 (64) | |
| moderate (ΙΙ) | 93 | 54 (58) | 39 (42) | |
| poor (ΙΙΙ) | 23 | 18 (78) | 5 (22) | |
| Clinical TNM stage | 0.001 | |||
| І | 44 | 18 (41) | 26 (59) | |
| ΙΙ | 54 | 32 (59) | 22 (41) | |
| ΙΙΙ-IV | 32 | 27 (84) | 5 (16) | |
| Estrogen receptor | 0.756 | |||
| - | 61 | 37 (61) | 24 (39) | |
| + | 69 | 40 (58) | 29 (42) | |
| Progesterone receptor | 0.835 | |||
| - | 75 | 45 (60) | 30 (40) | |
| + | 55 | 32 (58) | 23 (42) | |
| Her-2 expression | 0.888 | |||
| - | 50 | 30 (60) | 20 (40) | |
| + | 80 | 47 (59) | 33 (41) | |
| Menopause | 0.553 | |||
| No | 50 | 28 (56) | 22 (44) | |
| Yes | 80 | 49 (61) | 31 (39) | |
Abbreviations: TNM, tumor lymph-node metastasis.