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. Author manuscript; available in PMC: 2016 Dec 19.
Published in final edited form as: Gut. 2015 Jan 22;64(11):1732–1743. doi: 10.1136/gutjnl-2014-308820

Figure 4.

Figure 4

Effects of ABx and of ABx-resistant microbes on the host: (A) gene ontology categories over-represented in the genes of the subnetwork directly affected by ABx and by ABx-resistant microbiota. Size of the symbol represents enrichment fold; only most enriched categories are indicated. See also online supplementary figure S6; (B and C) mitochondrial staining (Mitotracker MFI normalised to the average MFI for each experiment), apoptosis (Annexin V) and cell viability (7AAD), in gut epithelial cells isolated from ABx-treated and control mice; (B) a single representative experiment; (C) summary graphs of 3–5 experiments; each symbol represents one mouse; median values are represented by horizontal lines; all comparisons significant at p<0.01. Ctrl, control; ABx, antibiotic-treated; MFI, mean fluorescent intensity.