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. 2016 Jul 27;1(5):344–359. doi: 10.1016/j.jacbts.2016.05.004

Figure 1.

Figure 1

Family Pedigrees TSFDC029, TSFDC031, and DNFDC057

Squares and circles indicate male and female subjects, respectively, and shading indicates a dilated cardiomyopathy phenotype. The arrowheads indicate probands. Plus and minus signs indicate carriers (+) or noncarriers (–) of the filamin C (FLNC) variant, respectively. Individuals II:2, III:4, and IV:1 in family TSFDC029 (A); individuals II:2, II:3, and III:1 in family TSFDC031 (B); and individuals II:1 and II:2 in family DNFDC057 (C) underwent whole exome sequencing, and are indicated by an ∗. Reported ages at death are indicated. (D) Electrocardiogram of subject TSFDC031 III:1 showing atrial fibrillation, which first occurred at the age of 21 years, and (E) the 2-dimensional echocardiogram images showing a mildly enlarged left ventricle with a left ventricular ejection fraction of 40% (age 36 years). LVEDD = left ventricular end-diastolic diameter; LVEDV = left ventricular end-diastolic volume; NCD = noncardiac death; SCD = sudden cardiac death.