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. Author manuscript; available in PMC: 2016 Dec 19.
Published in final edited form as: J Affect Disord. 2012 Jan 4;136(3):276–285. doi: 10.1016/j.jad.2011.11.036

Figure 3.

Figure 3

fMRI response (across all subjects) in each of the mPFC and sgPFC (a) and mPFC and the midbrain (b) are plotted in scatterplots. As seen, across groups, the mPFC-sgPFC response is highly coupled (confirmed by significant parametric regression). Across groups, the mPFC-midbrain response is not statistically coupled. Within HRS, a marginally significant negative coupling was observed suggesting that within the risk group, decreases in the mPFC response were associated with increases in the midbrain response. The overlaid density ellipses denote the density of data within each group. The dotted lines represent the results of spline interpolation (see Methods).