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. Author manuscript; available in PMC: 2017 Feb 15.
Published in final edited form as: Biochem Pharmacol. 2015 Dec 29;102:120–129. doi: 10.1016/j.bcp.2015.11.024

Fig. 2. Effect of sgk2 on the kinetics of hOAT4-mediated estrone sulfate transport.

Fig. 2

COS-7 cells were co-transfected with hOAT4 and the constitutive active form of sgk2 (CA-sgk2), or with hOAT4 and control vector. Initial uptake (3 min) of [3H] estrone sulfate was measured at the concentration of 0.1–10 μM. The data represent uptake into hOAT4-transfected cells minus uptake into mock cells (parental COS-7 cells). Values are means ± S.E. (n = 3). V, velocity; S, substrate concentration.