Table 1.

Neuromuscular Differential Diagnosis of “Failure to Wean From Ventilator.”

Motor neuron	Amyotrophic lateral sclerosis
	Poliomyelitis
	Guillain-Barre syndrome
	Critical illness polyneuropathy
	Critical illness polyneuropathy/myopathy
	Heavy metal toxicity
	Vasculitis
	Sarcoidosis
	Mononeuritis multiplex
Neuromuscular junction	Myasthenia gravis
	Neuromuscular blockade
	Lambert-Eaton myasthenic syndrome
	Botulinum toxicity
	Organophosphate toxicity
	Tetrodotoxin toxicity
Muscle	Rhabdomyolysis
	Mitochondrial myopathy
	Muscular dystrophy (eg, Myotonic dystrophy)
	Critical illness myopathy
	Acid maltase deficiency