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. 2016 Nov 14;8(12):1455–1469. doi: 10.15252/emmm.201606623

Figure EV3. Haplotype reconstruction for chromosome 10.

Figure EV3

Pedigree of the family with associated SNPs co‐segregating with the disease phenotype on chromosome 10 is represented. A total LOD score of 2.4 was identified between the flanking markers rs10509480 and rs10509758 and covered a 19.2 Mb region (chr10:85477515‐104681710; hg19). Filled symbol, LWD‐affected individual; symbol with a slash, deceased individual; slash, divorced; arrow, index patient. Colored chromosomal regions show traceable inheritance; red color regions, common haplotype co‐segregating with LWD; black lines, regions affected by a crossing over of unknown location.