Table S5.
Transcripts up-regulated by SFB only in S-IECs
Gene symbol | Mean expression, SFB | FC (BA/GF) | FC (SFB/GF) | FC (CH/GF) | P value (SFB/GF) |
H2-Ab1 | 864.3036064 | −0.324408008 | 3.202256552 | −1.521163198 | 0.029287522 |
Cd74 | 1,060.953036 | −0.290844415 | 3.092857404 | −1.862282404 | 0.049742042 |
H2-Eb1 | 322.4872275 | −0.112400906 | 2.164104766 | −0.693531819 | 0.003597187 |
Duox2 | 394.0993067 | −0.374474092 | 2.124737032 | −0.063176123 | 0.036657598 |
Ptk6 | 161.0831133 | −0.046995572 | 1.538463048 | 0.089640331 | 0.017248875 |
Eif5a | 1,789.643526 | 0.120287287 | 1.529926134 | 1.095302679 | 0.02900951 |
H2-DMa | 264.8838672 | −0.106568444 | 1.528387337 | −0.472898048 | 0.042888668 |
Tifa | 346.9209079 | −0.044207107 | 1.378854466 | 0.474167511 | 0.001057428 |
Tgtp1 | 148.0728486 | −0.3028355 | 1.366861107 | −0.763370742 | 0.042711938 |
Fut2 | 197.5802056 | −0.058696529 | 1.35730567 | −0.563572643 | 0.035898416 |
Psmb8 | 188.9961694 | −0.006376721 | 1.352040665 | −0.223229797 | 0.00267256 |
Ifi44 | 125.8182951 | 0.035393366 | 1.340878176 | −0.097493679 | 0.003726934 |
Ceacam10 | 428.9394856 | −0.092720287 | 1.307346599 | 0.237103626 | 0.00661915 |
Tnf | 147.9902206 | −0.179116865 | 1.263680788 | 0.204376572 | 0.008512408 |
Aldh2 | 445.8218127 | −0.033655259 | 1.224499514 | 0.631294649 | 0.03253427 |
Tfam | 194.231684 | 0.372769881 | 1.191469727 | 1.099633904 | 0.040669346 |
Hnrnpa0 | 121.1726667 | −0.02709674 | 1.133682113 | 0.490963364 | 0.048613253 |
Egr2 | 190.7897547 | −0.949001585 | 1.104808708 | −0.564805376 | 0.024198664 |
Tap1 | 294.5812203 | −0.084711809 | 1.066470549 | −0.331071012 | 0.009052195 |
H2-gs10 | 227.4762465 | −0.248390999 | 1.063330737 | 0.041060278 | 0.011698569 |
Ctss | 316.265238 | −0.103108139 | 1.059735387 | 0.040686248 | 0.043712925 |
Aldh1b1 | 1,181.764867 | −0.037675832 | 1.058305525 | 0.852257884 | 0.032582083 |
Psmb9 | 548.6074749 | 0.165314259 | 1.051021468 | 0.001376265 | 0.02211841 |
Tapbp | 926.2655353 | −0.060938018 | 1.049338905 | 0.174487227 | 0.041701087 |
Irgm2 | 171.433705 | 0.032383042 | 1.016344167 | −0.477902879 | 0.037031526 |
Alpk1 | 69.58134627 | −0.092606928 | 0.998955566 | 0.288675235 | 0.046187952 |
Akr1b8 | 100.4186767 | 0.152094934 | 0.997275275 | 0.156184575 | 0.032250424 |
Muc3 | 2,184.638659 | −0.53508588 | 0.980763441 | 0.086414667 | 0.021203783 |
Cd14 | 91.75652206 | 0.041077225 | 0.974792703 | 0.415377042 | 0.01424996 |
Lmna | 311.6235193 | −0.073409921 | 0.969193306 | 0.488004825 | 0.04298178 |
Alpk1 | 98.2839131 | 0.006417528 | 0.963044435 | 0.208108539 | 0.002476056 |
Alpk1 | 146.0583271 | 0.048409094 | 0.942259672 | 0.437523607 | 0.011033926 |
Slc44a4 | 927.7208509 | −0.059362631 | 0.926918264 | 0.181395166 | 0.048147332 |
Pim1 | 254.4340622 | −0.162779001 | 0.917345308 | 0.085768861 | 0.049978741 |
H2-D1 | 1,937.54729 | −0.011714872 | 0.911668241 | 0.107462751 | 0.020469557 |
Vwa5a | 223.007149 | −0.048470117 | 0.888440394 | 0.131417184 | 0.03464325 |
Slc35f2 | 508.3488969 | 0.106158917 | 0.871959093 | 0.613080369 | 0.007770322 |
2510006D16Rik | 649.7924109 | −0.12253481 | 0.870618264 | 0.436073434 | 0.033801007 |
Auh | 276.4461284 | −0.039341574 | 0.859762059 | 0.367844796 | 0.001951987 |
Gsr | 1,179.717001 | 0.151263834 | 0.853983138 | 0.388838783 | 0.031737108 |
Gm12250 | 159.6970376 | 0.144950057 | 0.841071934 | −0.421698502 | 0.006214875 |
Gstt3 | 492.295427 | −0.050177331 | 0.835219462 | 0.591549427 | 0.039551792 |
Thoc6 | 258.5126681 | 0.073053376 | 0.827155367 | 0.621163556 | 0.040358674 |
Acadl | 427.7414258 | 0.097334204 | 0.824597087 | −0.025807889 | 0.000242 |
Nox1 | 420.7207819 | −0.544232253 | 0.818516656 | −0.23672549 | 0.008838847 |
Trabd | 428.7785606 | 0.206983161 | 0.81770812 | 0.693625145 | 0.026975323 |
Cdc42ep1 | 125.1954183 | −0.078511793 | 0.812228257 | 0.372161391 | 0.007554632 |
Mknk2 | 427.8455383 | −0.048961505 | 0.808081014 | 0.517224158 | 0.040824685 |
Gabarapl1 | 159.4988978 | −0.386049463 | 0.806750452 | 0.053744159 | 0.030099425 |
Cd177 | 190.3525363 | −0.138960558 | 0.804304905 | 0.04765301 | 0.014124953 |
Rnf213 | 428.6160414 | 0.149077594 | 0.803138423 | 0.427420259 | 0.03015489 |
Tmem54 | 1,556.331592 | −0.080430896 | 0.80138319 | 0.144172177 | 0.047677122 |
Gpd1 | 958.6161025 | 0.078939306 | 0.799998057 | 0.763680793 | 0.01572532 |
Fos | 1,012.46335 | −0.502899921 | 0.799891127 | 0.033073799 | 0.037216162 |
Nans | 520.9687845 | −0.032188415 | 0.797706676 | 0.510260701 | 0.022532429 |
Cox15 | 354.4671488 | −0.078967981 | 0.78723932 | 0.294362139 | 0.04652294 |
Eif2s1 | 870.3708021 | 0.270712235 | 0.780815701 | 0.613135834 | 0.002927944 |
1110004F10Rik | 276.258603 | 0.136545142 | 0.779370563 | 0.234205413 | 0.026115963 |
Irgm1 | 436.9936141 | 0.022953476 | 0.767844473 | 0.032999897 | 0.043537383 |
Ctdsp2 | 354.6803291 | −0.134851284 | 0.762115889 | 0.349000016 | 0.040534857 |
Nrm | 264.3525319 | −0.107569376 | 0.758593624 | 0.364641645 | 0.027205895 |
Rnf213 | 475.7625362 | 0.153283375 | 0.755046347 | 0.288497253 | 0.029001776 |
Lonp1 | 225.368496 | −0.082415528 | 0.753098706 | 0.390154269 | 0.039925285 |
Dut | 293.3013282 | 0.1478784 | 0.749990752 | 0.521535105 | 0.038543958 |
Prmt1 | 184.8512311 | −0.068883333 | 0.748625298 | 0.436335165 | 0.049424595 |
Ubl4 | 377.5721773 | −0.08631798 | 0.74533314 | 0.494452358 | 0.039431507 |
Ppif | 1,484.442256 | −0.181518144 | 0.736359998 | 0.397556836 | 0.019067053 |
Rab22a | 346.7216227 | −0.058613386 | 0.73181034 | 0.512294298 | 0.040701397 |
Samm50 | 981.3431587 | 0.004678751 | 0.729188612 | 0.541250807 | 0.005356581 |
Rnf213 | 500.3337491 | 0.204938717 | 0.729139015 | 0.284488796 | 0.018276385 |
Ddah1 | 394.6985054 | −0.201062995 | 0.728563348 | −0.139752555 | 0.006829513 |
Psmd2 | 1,629.116733 | 0.182903541 | 0.725788525 | 0.639655525 | 0.038941761 |
Lasp1 | 1,438.808897 | −0.046897057 | 0.724701446 | 0.315574911 | 0.035365309 |
Leng8 | 398.088658 | −0.147218858 | 0.724057166 | 0.304223185 | 0.012437372 |
Kcnn4 | 497.9095778 | −0.305017138 | 0.722907244 | 0.230757235 | 0.034070832 |
Socs3 | 213.3785358 | 0.040385098 | 0.716144074 | −0.019219586 | 0.027892414 |
Kcnk5 | 229.8222278 | −0.19951165 | 0.715284854 | 0.323019117 | 0.003772795 |
Scpep1 | 701.0298425 | −0.091097416 | 0.71479258 | 0.33176566 | 0.033927504 |
Hnrnpa1 | 1,691.089506 | 0.076112414 | 0.714337572 | 0.411684837 | 0.044690053 |
Fen1 | 207.8829216 | 0.257123807 | 0.713508095 | 0.645303865 | 0.034303371 |
R3hcc1 | 213.7382317 | −0.409700376 | 0.712688034 | −0.049408817 | 0.021286932 |
Copg | 891.3751921 | 0.047894604 | 0.710999521 | 0.352746329 | 0.037563249 |
Slc25a39 | 1,294.016431 | 0.011854634 | 0.710766031 | 0.53880392 | 0.033789153 |
Aamp | 519.6517943 | 0.073177813 | 0.709429088 | 0.385657771 | 0.036701433 |
Fbln1 | 527.1451112 | −0.293228548 | 0.706770494 | 0.094155104 | 0.018277207 |
Aldh7a1 | 199.6616417 | −0.256083301 | 0.706430978 | 0.294917092 | 0.02794333 |
Tbcd | 453.2641058 | −0.057241827 | 0.705437646 | 0.360166169 | 0.038873727 |
Cops7a | 1,149.741735 | −0.111092425 | 0.703262746 | 0.440175499 | 0.024442374 |
Impa2 | 249.4182071 | 0.077742565 | 0.700950722 | 0.474141683 | 0.040908808 |
Racgap1 | 528.3065635 | −0.030730307 | 0.700852217 | 0.466463015 | 0.021909785 |
Etv3 | 485.2732922 | −0.106407706 | 0.699935981 | 0.299574569 | 0.006419214 |
Sema4a | 760.1822621 | −0.150575351 | 0.699101852 | 0.05214455 | 0.030507252 |
Pmpcb | 518.7810892 | 0.187429534 | 0.698939592 | 0.287910919 | 0.027711762 |
H2-Q7 | 1,971.686228 | −0.033540965 | 0.690903317 | 0.025694482 | 0.004849169 |
Hectd3 | 430.9718012 | −0.109229763 | 0.690883598 | 0.146149911 | 0.024814191 |
Srp9 | 499.0198435 | 0.229177668 | 0.688200498 | 0.334171806 | 0.044594811 |
Rnf5 | 886.4360861 | −0.01573157 | 0.682411901 | 0.385386178 | 0.039489694 |
Tmem159 | 224.6584435 | −0.054349086 | 0.680913795 | 0.487061289 | 0.007390561 |
Mmab | 188.3914654 | −0.32132729 | 0.679072169 | 0.182068085 | 0.003570257 |
B4galt1 | 484.955027 | 0.111191495 | 0.675134042 | 0.303147065 | 0.020525324 |
Mcm7 | 809.3391936 | 0.002188805 | 0.673962008 | 0.434255828 | 0.013275378 |
2810004N23Rik | 186.6069081 | 0.018845814 | 0.670973219 | 0.440425515 | 0.034863951 |
Gm9853 | 350.343605 | −0.076880902 | 0.670785426 | 0.554783111 | 0.025135628 |
Rnf213 | 637.7170264 | 0.135818983 | 0.668351521 | 0.286844412 | 0.023099091 |
Mlkl | 151.8417788 | 0.039600514 | 0.667837795 | −0.187098566 | 0.014360993 |
Dohh | 79.93536678 | −0.059310754 | 0.66723907 | 0.342580879 | 0.02297723 |
Stk40 | 394.1437763 | 0.003021076 | 0.666463647 | 0.292515622 | 0.043656577 |
Mll2 | 87.77335576 | 0.109687448 | 0.664809663 | 0.575329282 | 0.03633027 |
Got1 | 1,210.059853 | 0.029434154 | 0.664012926 | 0.367844574 | 0.016071957 |
Golm1 | 1,026.300637 | 0.061833541 | 0.663179322 | 0.497176818 | 0.009197693 |
Chmp1a | 1,101.3044 | −0.165412399 | 0.661201119 | 0.112992356 | 0.037081577 |
Casp7 | 1,343.017393 | −0.101534238 | 0.660842228 | 0.153197299 | 0.036818891 |
Snhg1 | 107.8751458 | 0.342038891 | 0.659426609 | 0.728286178 | 0.015673423 |
Cnbp | 1,197.039079 | 0.090710185 | 0.659226362 | 0.442899127 | 0.033526808 |
Rnf213 | 254.0058019 | 0.087598008 | 0.656994567 | 0.304157037 | 0.0423432 |
Rnps1 | 765.7892573 | −0.206239926 | 0.652304911 | 0.313675873 | 0.011386319 |
Ttc4 | 296.9581144 | −0.021245529 | 0.649211001 | 0.354772919 | 0.045727215 |
Dbnl | 366.8144839 | −0.044944534 | 0.646592237 | 0.273874227 | 0.043625112 |
Mcm2 | 594.1872909 | −0.017589881 | 0.646189203 | 0.592592361 | 0.007915774 |
Rnps1 | 684.9402054 | −0.208401579 | 0.645659064 | 0.294948937 | 0.013693934 |
Unc5cl | 252.9362913 | 0.082447253 | 0.644983456 | 0.451801592 | 0.012956353 |
H2-K1 | 1,368.187133 | −0.018428994 | 0.643732116 | 0.024828837 | 0.012258779 |
Kras | 629.1931375 | 0.088494776 | 0.643056201 | 0.303088339 | 0.02051213 |
Isyna1 | 603.2600294 | −0.177302398 | 0.638367971 | 0.577992681 | 0.036398881 |
Noxa1 | 256.9485434 | −0.206569569 | 0.637308355 | 0.504169302 | 0.016249313 |
Shmt2 | 438.1671668 | −0.091060342 | 0.636971684 | 0.407756037 | 0.026514947 |
Nop58 | 303.554552 | 0.100885414 | 0.635744513 | 0.587497909 | 0.000488 |
Atl3 | 355.8091855 | 0.189316164 | 0.633175638 | 0.638234261 | 0.039815571 |
D17H6S56E-5 | 1,106.335903 | −0.069207838 | 0.632635585 | 0.508384111 | 0.022594284 |
Usp19 | 373.2959307 | 0.057641983 | 0.63261347 | 0.57363622 | 0.038364891 |
Vars | 639.8954975 | −0.06370674 | 0.631092949 | 0.364381912 | 0.006650937 |
Acad8 | 278.8564257 | −0.057436283 | 0.630919079 | 0.41928084 | 0.048064907 |
Lmnb1 | 411.4337005 | 0.05995137 | 0.630150495 | 0.562437006 | 0.021640015 |
Acsf2 | 195.8420184 | −0.264737513 | 0.628705114 | −0.180684276 | 0.033104218 |
Snx17 | 468.1081772 | −0.053003167 | 0.62809884 | 0.462831237 | 0.008606001 |
Rad54l | 259.2303557 | 0.173002395 | 0.627591526 | 0.595451281 | 0.049746761 |
Slc35a4 | 333.2359761 | 0.077048315 | 0.623074016 | 0.489892598 | 0.000612 |
Acsf2 | 197.7962242 | −0.225709506 | 0.622492477 | −0.121141893 | 0.043280743 |
Psap | 2,745.853589 | −0.090384654 | 0.620567115 | 0.274588744 | 0.046600158 |
Ctdsp2 | 916.699924 | −0.196246003 | 0.620492826 | 0.119113471 | 0.003716511 |
Nup62 | 619.3168435 | −0.043234174 | 0.620223638 | 0.461350352 | 0.019059225 |
Abcb6 | 203.458556 | 0.008991337 | 0.619759588 | 0.484789377 | 0.014386861 |
Ppp2r4 | 365.9775948 | 0.068514234 | 0.619527862 | 0.492320706 | 0.016769666 |
Htra2 | 277.2271786 | −0.012135448 | 0.619131166 | 0.334845608 | 0.021588638 |
Aldh9a1 | 2,201.734416 | −0.124961377 | 0.617004325 | 0.312163687 | 0.015026998 |
Rnf213 | 322.0485884 | 0.043709194 | 0.616805024 | 0.183848045 | 0.030731796 |
Erbb3 | 1,475.562755 | −0.136046921 | 0.613193891 | 0.175663551 | 0.043574987 |
Nucb2 | 106.0905564 | 0.083630076 | 0.611634017 | −0.03008157 | 0.023765684 |
Eno1 | 2,254.463021 | 0.182980226 | 0.607740308 | 0.509971208 | 0.029883759 |
Med18 | 88.44012961 | 0.030032512 | 0.607380112 | 0.570561665 | 0.006240166 |
Manbal | 572.2236175 | −0.137865806 | 0.607070424 | 0.077584808 | 0.045687528 |
Ehd4 | 260.0985443 | 0.03585688 | 0.60636848 | 0.349965453 | 0.02878 |
Stat1 | 443.4290062 | 0.113087296 | 0.604897523 | 0.251959655 | 0.002445993 |
Stat3 | 688.5619236 | 0.076477235 | 0.604874347 | −0.071808598 | 0.007663359 |
Hyou1 | 882.3158196 | 0.324694142 | 0.604147114 | 0.698535354 | 0.005343729 |
Cdt1 | 375.4455878 | −0.114929499 | 0.603348393 | 0.357730751 | 0.030283926 |
Dusp5 | 388.669155 | −0.5278057 | 0.602567275 | −0.275468382 | 0.027346573 |
Grhpr | 411.0792627 | −0.051414792 | 0.602434861 | 0.278468251 | 0.015321714 |
Srp68 | 446.876007 | −0.01995338 | 0.600220985 | 0.5080635 | 0.011879957 |
Dhdds | 357.7781692 | 0.292109256 | 0.600124859 | 0.871087434 | 0.029011737 |
Abhd14b | 356.2234469 | −0.06764228 | 0.599412258 | 0.387927264 | 0.040367048 |
Tmem50a | 854.0278889 | −0.008021259 | 0.599229446 | 0.27154395 | 0.039130855 |
Hnrnpa1 | 1,302.407765 | 0.002947635 | 0.595822632 | 0.25907306 | 0.044027028 |
Hk2 | 243.0198342 | −0.046563933 | 0.595064847 | 0.377234187 | 0.031246932 |
Lysmd2 | 89.20163748 | 0.150543621 | 0.594789486 | 0.363204035 | 0.031877078 |
Afg3l1 | 260.7971973 | 0.042963439 | 0.593257537 | 0.313427813 | 0.010897723 |
Plekhb2 | 1,513.949932 | 0.000346045 | 0.592187847 | 0.373997045 | 0.02391808 |
Pttg1ip | 1,025.152765 | −0.19922309 | 0.591688742 | 0.348753223 | 0.028336477 |
Suv420h2 | 553.5969436 | 0.021210265 | 0.590706624 | 0.243571094 | 0.004588532 |
Slc39a7 | 481.7370152 | 0.063900487 | 0.589637545 | 0.327927016 | 0.029739369 |
Exph5 | 128.6397063 | −0.032969069 | 0.589389164 | 0.268808852 | 0.027005604 |
BC031781 | 227.5235025 | −0.137178336 | 0.587145375 | 0.390982787 | 0.02438911 |
Smu1 | 515.2426612 | 0.080531536 | 0.586560034 | 0.467572388 | 0.01434829 |
Tcof1 | 329.2185576 | −0.012537114 | 0.585094494 | 0.46523729 | 0.023529582 |
Log2 (FC) values are shown; P values are calculated by Student's t test. CH, Clostridium histolyticum.