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Mean values for the parameters obtained from fitting a Boltzmann function to the peak Ca2+ release flux versus voltage data
| Boltzmann parameters | WT, n = 20 | KO, n = 13 | WT PtdIns 3-K block, n = 17 | KO WT PtdIns 3-K block, n = 12 |
| Maximal release flux, µM·ms−1 | 50.0 ± 5.4 | 19.0 ± 2.9 | 51.5 ± 4.9 | 34.1 ± 3.5 |
| Midactivation voltage, mV | −5.9 ± 1.7 | −5.9 ± 2.1 | −8.2 ± 2.6 | −0.1 ± 2.1 |
| Steepness factor, mV | 7.6 ± 0.4 | 6.5 ± 0.5 | 7.4 ± 0.5 | 9.6 ± 0.8 |
Data are mean ± SEM.
