Vangl2f/f and Vangl2d/d females have comparable ovarian steroid hormone levels and patterns of uterine PR and ERα expression. (A) Serum progesterone levels on days 4, 8, and 12 of pregnancy. Data are shown as mean ± SEM; P > 0.05. (B) Serum estradiol-17β levels on days 4, 8, and 12 of pregnancy. n = 4 females. Data are shown as mean ± SEM; P > 0.05. (C) Vangl2 expression is very low in ovarian follicular cells on day 4. (D) PR and ERα localization patterns are comparable in Vangl2f/f and Vangl2d/d uteri on day 4. (Scale bars, 100 µm.)