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EGFR signaling is important for articular cartilage structure. Average thicknesses of uncalcified (Uncal. Th.), calcified (Cal. Th.), and total (Total, Th.) articular cartilage were quantified in the tibial plateau of 2- and 6-mo-old WT, Wa5, and Egfr CKO mice. n = 6 per age per genotype. *P < 0.05, $P < 0.01, &P < 0.001 vs. WT; #P < 0.05, ^P < 0.001 vs. Wa5.
