Table S1.

Real-time PCR primer sequences used in this study

Gene	Forward primer	Reverse primer
β-actin	5′-TCCTCCTGAGCGCAAGTACTCT-3′	5′-CGGACTCATCGTACTCCTGCTT-3′
Col2a1	5′-GCTCCCAGAACATCACCTACCA-3′	5′-TCATTGGAGCCCTGGATG-3′
Aggrecan	5′-CCTTGTCACCATAGCAACCT-3′	5′-CTACAGAACAGCGCCATCA-3′
Prg4	5′-TCCGAGAACCATGGGGTGG-3′	5′-TCTCCCTGCACAGCTTGATA-3′
Ggpdh	5′-GCAAAGTGGAGATTGTTGCCAT-3′	5′-CCTTGACTGTGCCGTTGAATTT-3′
Egfr	5′-GGAAACCGAAATTTGTGCTACG-3′	5′-GCCTTGCAGTCTTTCTCAGCTC-3′
Erb2	5′-CAGTGAGGATCCCACATTAC-3′	5′-CTCTGGCTGGTTCACATAC-3′
Tgfα	5′-TGTGCTGATCCACTGCTGTCA-3′	5′-AGCAAGCAGTCCTTCCCTTCA-3′
Hbegf	5′-ACAAGGACTACTGCATCCACGG-3′	5′-AGAGTCAGCCCATGACACCTGT-3′
Epiregulin	5′-TTCAGATGGAAGACGATCCCC-3′	5′-TGTCCACCAGGTAGATGCACTG-3′
Egf	5′-CATCCATTGGCAAAACCAGGT-3′	5′-TCACGACACAAACACCGAGCT-3′
Betacellulin	5′-GCCCCAAGCAGTACAAGCATT-3′	5′-AAACAGGTCCACTCGCTCACA-3′
Amphiregulin	5′-GCATCGGCATCGTTATCACAG-3′	5′-GCGTGCACAGTCCCATTTTC-3′
β-actin (bovine)	5′-TGGCGCTTGACTCAGGATTT-3′	5′-AATCAAGTCCTCGGCCACACT-3′
Prg4 (bovine)	5′-TGAACCGACTCCTACCTCTTTA-3′	5′-CAGCATCTCCATCCTCATTCTC-3′

All primers are designed for mouse genes, except the last two pairs, which are designed for bovine genes.