Table 3. Diagnostic performance of magnifying endoscopy for H. pylori infection.
| Study group | Number of studies | Diagnostic performance | I2 for DOR | |||||
|---|---|---|---|---|---|---|---|---|
| Sensitivity 95%CI | Specificity 95%CI | LR+ 95%CI | LR- 95%CI | DOR 95%CI | AUC | |||
| All | 18 | 0.89 (0.87–0.91) | 0.82 (0.79–0.85) | 5.16 (3.32–8.02) | 0.11 (0.07–0.18) | 59.58 (30.63–115.88) | 0.9461 | 67.10 |
| Observed site | ||||||||
| Antrum | 5 | 0.82 (0.78–0.86) | 0.72 (0.66–0.78) | 2.99 (1.39–6.44) | 0.25 (0.15–0.40) | 14.72 (8.86–24.47) | 0.8611 | 0.00 |
| Corpus | 11 | 0.92 (0.90–0.94) | 0.86 (0.82–0.88) | 5.96 (3.88–9.15) | 0.06 (0.03–0.13) | 127.38 (48.29–336.05) | 0.9702 | 70.60 |
| Diagnostic criterion | ||||||||
| “pit plus vascular pattern” in corpus | 6 | 0.96 (0.94–0.97) | 0.91 (0.87–0.93) | 9.56 (4.72–19.34) | 0.05 (0.03–0.08) | 203.69 (77.11–538.02) | 0.9872 | 29.70 |
| Endoscopy mode | ||||||||
| White light endoscopy | 11 | 0.90 (0.87–0.91) | 0.81 (0.77–0.84) | 4.88 (2.63–9.08) | 0.09 (0.04–0.19) | 75.28 (30.11–188.21) | 0.9576 | 68.60 |
| Chromoendoscopy | 7 | 0.87 (0.83–0.91) | 0.85 (0.80–0.88) | 5.44 (3.54–8.35) | 0.13 (0.06–0.26) | 46.52 (15.68–138.03) | 0.9238 | 67.20 |
LR+, positive likelihood ratio; LR-, negative likelihood ratio; DOR, diagnostic odds ratio; AUC, area under the curve; CI, confidence interval.