Fig 4. Effect of LRIM1 silencing in A. albimanus mosquitoes on its infection with P. falciparum Pfs47 NF54 V247A and I248L.

Effect of silencing the leucine-rich repeat immune protein 1 (LRIM1) in A. albimanus on infection with NF54 Pfs47 haplotypes V247A and I248L. Each dot represents the number of parasite on an individual mosquito and the median is indicated with a black line (n = number of midguts examined). The orange area of the pie charts indicates the prevalence of infection. All parasite phenotypes were confirmed in two independent experiments. Median number of oocysts were compared using the Mann–Whitney test. ****P < 0.0001.