Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
In the proposed roadmap of HSPC development, Stage I refers to the differentiation of ESCs into HM/E, which required Group XII genes. The transition from HM/E, which is dependent on Group IV genes, is denoted as Stage II. Group X genes are specifically required for HSPC specification, indicated as Stage III. See text for details.
