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Genealogy tree of the EOAD patients with PSENl T1161 mutation. The symbols filled with black represent the patients with clinical Alzheimer’s disease, while the gray symbols correspond to the family members with mild cognitive impairment (MCI). The arrow indicates the proband being studied here. The history of dementia was not available in first generation of the genealogy tree.
Abbreviation: EOAD, early-onset Alzheimer’s disease.
