TABLE 1.
Percent BrdU incorporation in EGFR- and MycER-overexpressing cells
| Virus | % BrdU incorporation in the presence of:
|
P | |
|---|---|---|---|
| FN | FN + EGF | ||
| No virus | 5.9 ± 1.2 | 15.9 ± 1.3 | 0.0008 |
| pLPCX vector | 7.2 ± 0.7 | 21.1 ± 3.4 | 0.0016 |
| pLPCX-EGFR1 | 19.9 ± 4.5 | 20.5 ± 3.9 | 0.1999 |
| pLPCX-EGFR1 | 15.3 ± 2.8 | 15.5 ± 1.9 | 0.4666 |
| pLPCX-EGFR5 | 13.0 ± 0.2 | 15.2 ± 3.0 | 0.1810 |
| pCLXSN-MycER | 7.7 ± 2.4 | 34.4 ± 3.8 | 0.0015 |
| pCLXSN-MycER + Tx | 28.6 ± 4.0 | 40.1 ± 5.6 | 0.0321 |
| pCLXSN-MycER + Tx | 24.5 ± 1.5 | 32.9 ± 4.5 | 0.0451 |
| pCLXSN vector | 2.9 ± 0.1 | 14.3 ± 0.9 | 0.0001 |
| pCLXSN-CycD1 | 3.8 ± 0.1 | 18.5 ± 4.1 | 0.0054 |
| pCLXSN-CycD1 | 4.0 ± 1.6 | 14.1 ± 1.2 | 0.0004 |