Serum samples from sham, vehicle, IgG control, and anti-OPN Ab groups were collected to measure (A) BUN and (B) creatinine. Data are expressed as mean ± SEM (n=7–9 mice/group) and compared by one-way ANOVA by SNK method. *p<0.05 vs. sham; #p<0.05 vs. vehicle; ψp<0.05 vs. IgG. BUN, blood urea nitrogen; OPN, osteopontin.