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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Shock. 2017 Jan;47(1):52–60. doi: 10.1097/SHK.0000000000000721

Figure 3. Neutralization of OPN reduces novel renal injury markers.

Figure 3

Renal tissue from sham, vehicle, IgG control, and anti-OPN Ab treated mice were collected to measure (A) NGAL and (B) KIM-1 mRNA by qRT-PCR. Their expression levels were normalized to β-actin, and sham was designated as 1 for comparison. Data are expressed as mean ± SEM (n=6–8 mice/group) and compared by one-way ANOVA by SNK method. *p<0.05 vs. sham; #p<0.05 vs. vehicle; ψp<0.05 vs. IgG. OPN, osteopontin; NGAL, neutrophil gelatinase-associated lipocalin; KIM-1 kidney injury molecule-1.