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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Resuscitation. 2016 Sep 22;110:154–161. doi: 10.1016/j.resuscitation.2016.09.015

Table 4.

Sensitivity analyses testing sequential intervals of ten compressions/min compared to the reference range of 100-120 compressions/min: multivariable logistic regression models testing (a) successful return of spontaneous circulation as the dependent variable, and (b) good neurological outcome [defined as Cerebral Performance Category (CPC) < 3 at hospital discharge] as the dependent variable.

a)
Variables Odds Ratio 95% LCI 95% UCI Standard Error p-value
Chest compression rate*
  100 – 120 Reference
  121 – 130 5.17 1.38 19.45 3.50 0.015
  131 – 140 4.21 1.28 13.84 2.56 0.018
  141 – 150 2.03 0.61 6.78 1.25 0.247
  > 150 1.78 0.52 6.15 1.13 0.360
Age (decile) 1.09 0.89 1.34 0.11 0.393
VT/VF initial rhythm 1.90 0.92 3.90 0.70 0.082
Charlson comorbidity score 1.15 0.86 1.54 0.17 0.357
Chest compression fraction 2.49 0.85 7.33 1.37 0.097
Monitored bed 0.73 0.38 1.41 0.25 0.349
b)
Variables Odds Ratio 95% LCI 95% UCI Standard Error p-value
Chest compression rate*
  100 – 120 Reference
  121 – 130 3.92 0.36 43.04 4.79 0.264
  131 – 140 2.19 0.23 21.21 2.54 0.498
  141 – 150 1.10 0.10 11.91 1.33 0.940
  > 150 1.51 0.15 15.65 1.80 0.729
Age (decile) 0.98 0.70 1.37 0.17 0.893
VT/VF initial rhythm 7.86 2.72 22.71 4.26 0.000
Charlson comorbidity score 0.61 0.37 1.02 0.16 0.057
Chest compression fraction 0.59 0.14 2.51 0.43 0.470
Monitored bed 0.72 0.21 2.48 0.46 0.609
*

Mean chest compression rate for duration of cardiopulmonary resuscitation (compressions/minute); LCI, lower confidence interval; UCI, upper confidence interval; VF, ventricular fibrillation; VT, ventricular tachycardia.