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Expression of small t antigen does not affect PDK-1 activity. 3T3-L1 adipocytes were infected with either control virus or small-t-antigen-encoding adenovirus (ST). Whole-cell lysates were prepared and assayed for PDK-1 activity as described in Materials and Methods. Data are presented as the increase in PDK-1 activity (n-fold) compared to unstimulated control cells and represent the mean ± SE of results from three independent experiments.
