Table 3. Multiple linear regression analyses in patients with type 2 diabetes mellitus and advanced diabetic retinopathy.
| Variable | uACR | eGFR | ||
|---|---|---|---|---|
| β | P value | β | P value | |
| HbA1c-SD | ||||
| Model 1 | 0.56 | <0.01 | −4.24 | 0.05 |
| Model 2 | 0.50 | <0.01 | −4.99 | 0.02 |
| Model 3 | 0.22 | 0.26 | −5.04 | 0.02 |
| Adj-HbA1c-SD | ||||
| Model 1 | 0.56 | <0.01 | −4.23 | 0.05 |
| Model 2 | 0.50 | <0.01 | −4.97 | 0.02 |
| Model 3 | 0.23 | 0.24 | −5.06 | 0.02 |
| HbA1c-CV | ||||
| Model 1 | 0.64 | <0.01 | −5.87 | 0.01 |
| Model 2 | 0.57 | <0.01 | −7.01 | <0.01 |
| Model 3 | 0.23 | 0.25 | −5.14 | 0.02 |
| TG/HDL-C ratio | ||||
| Model 1 | 0.80 | <0.01 | −7.26 | <0.01 |
| Model 2 | 0.77 | <0.01 | −8.28 | <0.01 |
| Model 3 | 0.58 | <0.01 | −6.66 | <0.01 |
Model 1: non-adjusted; model 2: adjustments for age and sex; model 3: model 2 plus adjustments for mean systolic blood pressure (SBP), diabetes duration, hemoglobin, mean HbA1c, TG/HDL-C ratio; model 3a: model 2 plus adjustments for mean SBP, diabetes duration, hemoglobin, mean HbA1c, HbA1c-SD.
uACR, urine albumin/creatinine ratio; eGFR, estimated glomerular filtration rate; HbA1c, glycosylated hemoglobin; SD, standard deviation; Adj, adjusted; CV, coefficient of variation; TG, triglyceride; HDL-C, high density lipoprotein cholesterol.