Table 4. Multivariate logistic regression analyses of HbA1c variability or TG/HDL-C ratio as predictors of the severe diabetic kidney disease in patients with type 2 diabetes mellitus and advanced diabetic retinopathy.
| Variable | OR (95% CI)a | |||
|---|---|---|---|---|
| HbA1c-SD | Adj-HbA1c-SD | HbA1c-CV | TG/HDL-C ratio | |
| Model 1 | 1.92 (1.24–2.97) | 1.91 (1.24–2.97) | 2.26 (1.38–3.69) | 2.43 (1.58–3.74) |
| Model 2 | 2.03 (1.29–3.18) | 2.02 (1.29–3.17) | 2.47 (1.49–4.11) | 2.65 (1.69–4.14) |
| Model 3 | 2.22 (1.17–4.22) | 2.22 (1.17–4.21) | 2.24 (1.18–4.25) | - |
| Model 3a | - | - | - | 2.51 (1.46–4.30) |
Model 1: non-adjusted; model 2: adjustments for age and sex; model 3: model 2 plus adjustments for mean systolic blood pressure (SBP), diabetes duration, hemoglobin, mean HbA1c, TG/HDL-C ratio; model 3a: model 2 plus adjustments for mean SBP, diabetes duration, hemoglobin, mean HbA1c, HbA1c-SD.
HbA1c, glycosylated hemoglobin; TG, triglyceride; HDL-C, high density lipoprotein cholesterol; OR, odds ratio; CI, confidence interval; SD, standard deviation; Adj, adjusted; CV, coefficient of variation.
aAll P<0.05.