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. 2016 Dec 20;7:2006. doi: 10.3389/fmicb.2016.02006

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Copyright © 2016 Barreto-Santamaría, Curtidor, Arévalo-Pinzón, Herrera, Suárez, Pérez and Patarroyo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Peptide 35409 action on bacterial DNA. Peptide 35409-DNA binding capability was measured by gel retardation assay of plasmid DNA electrophoretic run on agarose gel. (A) Peptide concentrations were 0, 11, 22, 44, and 88 μM (as shown in the upper part of each well). For in vivo bacterial filamentation assay, (B) untreated bacteria were used as negative control, (C) ciprofloxacin-treated bacteria as positive control and (D) bacteria incubated with peptide 35409 (22 μM). Bacterial elongation can be seen regarding treatment with peptide 35409.