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. 2016 Nov 4;8(4):213–222. doi: 10.1038/ijos.2016.33

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Copyright © 2016 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Gross view and dimension analyses of in vivo engineered tendons. (a) Gross view of DPSC-engineered tendon complexes at weeks 8 and 14 after implantation. After 2 weeks of static stretch in vitro, the engineered tendon was transplanted into the mice with (a1, a2) and without (a3, a4) mechanical loading for 8 and 14 weeks. (b, c) Quantitative analyses of engineered tendon complexes on central thickness and width. There are significant differences in these parameters among different groups (P<0.01) (n=5; P-values are provided in Supplementary Data S4). * and *** respectively indicates significant difference between loaded and non-loaded groups with P<0.05 and P<0.001. DPSCs, dental pulp stem cells.