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. 2016 Nov 4;8(4):213–222. doi: 10.1038/ijos.2016.33

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Copyright © 2016 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Immunohistochemical staining reveals the expression of crucial tendon-related molecules in the tendons engineered by DPSCs. (a) col I; (b) Col VI; (c) SCX; (d) TNC; (e) TNMD; (f) EYA2. Col I exhibited more organized expression (aligned or bundled) (arrows in a1 and a3) in the loaded groups than that in the unloaded groups after 8 and 14 weeks postimplantation. The other molecules exhibit an expression pattern similar to the loaded groups. Original magnification: × 400; bar=50 μm. DPSCs, dental pulp stem cells; EYA2, eye absent 2; SCX, scleraxis; TNC, tenascin-C; TNMD, tenomodulin.