Table 1.
Summary table of examinations and measurements
| Domain | Parameter | Instrument/technique | Assessing person | Time needed (minutes) |
|---|---|---|---|---|
| Administrative/general/social | Name | Self-administered questionnaire | Participant | 10 |
| Address | ||||
| Phone number | ||||
| Birth date (dd/mm/yy, time of day) | ||||
| Sex | ||||
| Birth weight (based on birth record) | ||||
| Place of origin | ||||
| Living situation | ||||
| Education | ||||
| Occupation | ||||
| Means of transport used | ||||
| Social ties | ||||
| Immunisation status | ||||
| Medical history | Symptoms (NYHA-class, AP CCS, pain) | Self-administered questionnaire (controlling by physician) | Participant/physician | 10 |
| Cardiovascular risk factors | ||||
| Previous cardiovascular events | ||||
| Previous surgical interventions | ||||
| Drugs (prescribed and over-the-counter) | ||||
| Alcohol, smoking | ||||
| Falls history | ||||
| Sleep disorders | ||||
| Anthropometry | Body weight | Balance (measurement in underwear) | Study nurse | 10 |
| Body height | Measure | |||
| Circumference of upper and lower extremities | Tape measure | |||
| Circumference of thighs, waist and hip | Tape measure | |||
| Skinfold thickness (trunk/extremities) | Caliper (Harpenden) | |||
| Body composition | Segmental bio-impedance (Tanita SC-240) | |||
| Cardiovascular system | Resting blood pressure/heart rate (sitting position and 1–3 min after standing up) | Oscillometric device (Omron 705IT)31 | Study nurse/physician | 25 |
| Central blood pressure and pulse wave velocity | Oscillometric device (TensioMed Arteriograph)32 | |||
| Home blood pressure measurement | Oscillometric device (Takeda UA-651)33 | |||
| Ambulatory blood pressure measurement | Oscillometric device (Takeda TM-2430)34 | |||
| Heart rate, PQ, QRS, QT, ST,Q | Normal ECG (Schiller AT02) | |||
| Pulse wave analysis | Tonometer (PulsePen, Diatecne)35 | |||
| Heart sounds, electromechanical activation time | Audicor36 37 Holter recording (24 hours) | |||
| Brain | Vision | Jaeger test38 | Study nurse | 20 |
| Hearing | Whisper test39 | |||
| Cognition (participants ≥50 years) | MMSE40 Verbal fluency Clock drawing test41 |
|||
| Executive function | Trail making test B42 | |||
| Reaction time | Computer-based tool | |||
| Lung | Pulmonary function | Peak flow O2 saturation Lung function (MIR Spirobank)43 |
Study nurse | 2 |
| General physical performance | Physical activity | Physical activity questionnaire | Study nurse/physician | 12 |
| Walking speed | 2 minute walking test44 | |||
| Arm strength | Handgrip test45 | |||
| Leg strength | Chair stand test46 | |||
| Balance | 4-stage balance test47 | |||
| ADL | Basic and instrumental ADL48 49 | |||
| Nutritional status | Weight loss | Self-report question | Participant/physician | 3 |
| Food frequency | Food frequency questionnaire | |||
| Consumer behaviour and food security | Consumer behaviour/food security questions | |||
| Emotional status | Depression (participants ≥18 years) | Depression screening questionnaire50 | Physician | 10 |
| Anxiety (participants ≥18 years) | Anxiety screening questionnaire50 | |||
| Self-perceived health (participants ≥18 years) | ||||
| Blood sample (only participants ≥18 years, voluntary) | Red and white cell count | Study nurse | 5 | |
| Sodium, potassium | ||||
| Creatinine | Blood sample in fasting state, measurement in validated laboratory | |||
| Aspartate, transaminase, albumin | ||||
| lipids, glucose/HbA1c | ||||
| Iron status (ferritin, TIBC) | ||||
| TSH | ||||
| Metabolomics, proteomics, genomics | Blood sample (50 mL) in heparin-free tube, processed immediately for serum collection, aliquoting and storage in RNase-free cryotubes in a sample bank at −80° for later analysis. All necessary preanalytical precautions will be implemented. | |||
| Urine sample (only participants ≥18 years, voluntary) | Proteinuria | Urine sample with test strip | Study nurse | 3 |
| Glucosuria | ||||
| Erythrocyturia |
ADL, activities of daily living; AP CCS, Canadian Cardiovascular Society grading of angina pectoris; HbA1c, glycated haemoglobin; NYHA, New York Heart Association; MMSE, Mini Mental State Examination; TIBC, total iron binding capacity; TSH, thyroid stimulating hormone.