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. 2016 Nov 29;6(11):e012486. doi: 10.1136/bmjopen-2016-012486

Table 3.

Incidence and HRs (95% CIs) of end-stage renal disease in different subgroups according to the baseline cardiovascular health score

10–14 (n=35 810) 5–9 (n=53 815) 0–4 (n=1818) One score decrease (n=91 443) p Value for trend p Interaction*
Sex 30 (0.43)
7.25
1.25 (0.71 to 2.20)
<0.001
 Women, case number 29 (0.24)   59 (0.31)
Cumulative incidence/1000 2.60   3.34
 HR‡ 1   1.19 (1.03 to 1.39) 0.017
 Men, case number 48 (0.20) 155(0.33) 11 (0.63) 214 (0.29)
 Cumulative incidence/1000 2.20 3.79 6.75 3.34
 HR‡ 1 1.59 (1.15 to 2.22) 2.90 (1.48 to 5.69) 1.20 (1.12 to 1.29) <0.001
Age 2.20 3.79 6.75 3.34 <0.001
 ≤60 years, case number 62 (0.21) 150 (0.36) 11 (0.71) 223 (0.31)
 Cumulative incidence/1000 2.35 4.12 7.70 3.51
 HR‡ 1 1.50 (1.10 to 2.05) 2.79 (1.43 to 5.46) 1.19 (1.11 to 1.28) <0.001
 >60 years, case number 15 (0.22) 35 (0.28) 50(0.26)
 Cumulative incidence/1000 2.28 3.84 2.82
 HR‡ 1 1.56 (0.90 to 2.72) 1.14 (0.71 to 1.87) 0.11

*p Value for interaction between studied factors and exposure status.

‡Adjusted for age (years), sex, education level (elementary school, high school or college or above), income level (income >800 RMB/month, income ≤800 RMB/month), alcohol consumption (never, past, current, <1 times/day or current, 1+ times/d), C reactive protein blood concentration (quartile 1) and estimated glomerular filtration rate.