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. 2016 Dec 16;6(12):e012040. doi: 10.1136/bmjopen-2016-012040

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

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The effect of the distribution of resistance on the EOI. In each case, there are D_y=3 treatment options. When all drugs provide full coverage EOI_y=D_y=3 (right column). Reducing the average coverage has the largest effect when all drugs provide the same coverage (top row), and the smallest effect when drugs provide full coverage (bottom row). EOI, Empiric Options Index.

Inline graphic — The effect of the distribution of resistance on the EOI. In each case, there are D_y=3 treatment options. When all drugs provide full coverage EOI_y=D_y=3 (right column). Reducing the average coverage has the largest effect when all drugs provide the same coverage (top row), and the smallest effect when drugs provide full coverage (bottom row). EOI, Empiric Options Index.