Table 1.

Overview of study methodology within each nation

	England (cohorts 1 and 4)	Wales (cohorts 2 and 5)	Northern Ireland (cohorts 2 and 5)	Scotland (cohorts 2 and 5)	Normative study (cohort 3)
Data source	Cancer registry	Cancer registry	Cancer registry	Hospital admissions	BSO
Confirmation of diagnosis and eligibility	Prostate MDT lead	Prostate MDT lead	Prostate MDT lead plus nurse check for unstaged cases	Hospital admission for prostate cancer plus cancer registration in relevant time period
Exclusions	Men eligible for NPCA /true NTH	Men eligible for NPCA		List from protocol	Men with previous prostate cancer
Death checks	NHS Digital	NHS Digital	BSO	NRS/NHSCR/CHI	BSO
Survey mail-out	Picker	Picker	Cancer registry	Picker	Picker
Language	English	English/Welsh	English	English
Survey dates	Cohort 1: November 2015–February 2016 Resurvey: November 2016–February 2017 Cohort 4: January 2017–March 2017	Cohort 2: June 2016–August 2016 Resurvey: June 2017–August 2017 Cohort 5: January 2017–March 2017			May 2016–July 2016
Estimated survey numbers*	Cohort 1: n=60 000 Resurvey: n=42 000 Cohort 4: n=15 000	Cohort 2: n=4000 Resurvey: n=2800 Cohort 5: n=2000	Cohort 2: n=2000 Resurvey: n=1400 Cohort 5: n=1000	Cohort 2: n=3600 Resurvey: n=2500 Cohort 5: n=1800	n=4000
Data linkages	Cancer registration; hospital admissions; radiotherapy; patient experience survey; end-of-life care	Cancer registration; hospital admissions; radiotherapy	Cancer registration; hospital admissions; radiotherapy	Cancer registration; hospital admissions; radiotherapy (linkage will only be possible where responding patients have given their consent)
Telephone interviews	Cohort 1: n=120 Follow-up interviews: n=60	Cohort 2: n=20	Cohort 2: n=20	Cohort 2: n=20	Not applicable to this cohort

*Estimates represent the total number of men eligible for inclusion (before death checks); resurvey estimates are based on a 70% response to first surveys.