Table 3.
List of the top 15 pregnancy-depressed pouch tissue genes
| Gene ID | Fold change | CPM | p value | Gene description | KO ID |
|---|---|---|---|---|---|
| SSCG00000006879 | 27.36 | 56.49 | 7.91E-43 | Serine/threonine-protein kinase WNK2 | K08867 |
| SSCG00000018539 | 12.37 | 15.96 | 2.04E-26 | FXYD domain-containing ion transport regulator 12 | |
| SSCG00000007973 | 4.73 | 53.34 | 1.66E-24 | A disintegrin and metalloproteinase with thrombospondin motifs 6, partial | K08621 |
| SSCG00000013585 | 10.78 | 19.10 | 1.07E-23 | Tetratricopeptide repeat protein 18 | |
| SSCG00000005985 | 214.58 | 652.27 | 7.29E-23 | patristacin, partial | K08076 |
| SSCG00000008728 | 14.12 | 6.03 | 2.22E-22 | Uridine-cytidine kinase-like 1 | K00876 |
| SSCG00000000969 | 4.32 | 19.82 | 1.25E-17 | ras-like protein family member 11A | K07852 |
| SSCG00000017729 | 6.14 | 359.52 | 1.71E-17 | nidogen-2-like isoform X5 | K06826 |
| SSCG00000004506 | 6.00 | 12.98 | 4.08E-17 | syntaxin-2-like isoform X1 | K08486 |
| SSCG00000010275 | 14.47 | 3.28 | 1.00E-16 | acid-sensing ion channel 1 | |
| SSCG00000016046 | 6.75 | 8.51 | 1.51E-16 | leucine-rich repeat-containing protein 4-like | K16351 |
| SSCG00000014649 | 10.15 | 7.67 | 1.77E-16 | homeobox protein MSX-2-like | K09341 |
| SSCG00000019217 | 66.66 | 3.26 | 1.82E-16 | leucine-rich repeat-containing protein 3-like | |
| SSCG00000007661 | 5.19 | 24.20 | 2.23E-16 | cytochrome P450 27C1-like | K17951 |
| SSCG00000005388 | 19.81 | 1.44 | 5.60E-16 | glutamate receptor ionotropic, delta-2 isoform X5 | K05207 |
Included are the fold change (non-pregnant/pregnant), average expression level across 12 pouch libraries in copies per million (CPM), edgeR negative binomial exact test p value, gene description from top BLASTP hit, and the assigned KEGG orthology ID for each pipefish gene. See Additional file 2 SH2 for the full list