Table 3.

SPIRIT study calendar (second 12 weeks) for VO₂max non-responders after the first 12-week intervention

			Exercise intervention
Point of time:	Pre-intervention	Baseline	Time 0	Week 4	Week 8	Week 12	12-week analysis
Pre-intervention
Switch of experimental group	x
Testing
Height		x		x	x	x
Weight		x		x	x	x
Resting heart rate		x		x	x	x
Resting blood pressure		x		x	x	x
Waist circumference		x		x	x	x
Low-density lipoprotein		x
High-density lipoprotein		x
Triglycerides		x
Blood glucose		x
Maximal exercise test		x		x	x	x
Verification test		x		x	x	x
3-day nutrition recall		x				x
Analysis
Incidence of response							x

SPIRIT Standard Protocol Items: Recommendations for Interventional Trials, VO2max maximal oxygen uptake