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. 2016 Dec 19;9:41. doi: 10.1186/s13040-016-0118-0

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — INO representation of interaction types. a INO representation of ‘regulation of transcription’. Equivalent and subclass axioms are defined for this class. As shown in the figure, INO is aligned with BFO as its upper level ontology. The annotated literature mining keywords and keyword dependency patterns for the INO class are highlighted with oval circle. b INO representation of ‘negative regulation of transcription by binding to promoter’. In addition to its subclass definitions, this INO terms also inherits many axioms defined in different levels of its ancestor terms