Table 5.
Secondary metabolite biosynthesis gene clusters identified in the genome of Actinoalloteichus hymeniacidonis DSM 45092 using antiSMASH 3.0.4 software followed by manual curation
| No | Cluster type | Presence in another bacterium# | Putative product |
|---|---|---|---|
| 1 | Ectoine | Saccharopolyspora rectivirgula DSM 43113 | Ectoine |
| 2 | NRPS-PKSI | Nonomuraea candida DSM 45086 | NRS peptide-polyketide hybrid |
| 3 | Ladderane | Saccharomonospora viridis DSM 43017 | Ladderane |
| 4 | NRPS-PKSI | - | NRS peptide-polyketide hybrid |
| 5 | Ectoine | multiple Actinoalloteichus spp. | Ectoine |
| 6 | Lassopeptide | - | Lassopeptide |
| 7 | Terpene | Kribbella flavida DSM 17836 | Terpenoid |
| 8 | PKSII | - | Aromatic polyketide |
| 9 | Terpene | - | Terpenoid |
| 10 | Siderophore | Saccharomonospora paurometabolica YIM 90007 | Siderophore |
| 11 | Terpene | Actinosynnema mirum DSM 43827 | Carotenoid |
| 12 | PKSIII | - | Stilbene-like polyketide |
| 13 | NRPS-PKSI | Streptomyces sp. NTK 937 | Polycyclic tetramate macrolactam |
| 14 | NRPS | Streptomyces sp. SirexAA-E | Coelibactin |
| 15 | PKSI | - | 34-membered macrocyclic lactone |
| 16 | NRPS-PKSI | Streptomyces bingchenggensis BCW-1 | NRS peptide-polyketide hybrid |
| 17 | Terpene | - | Terpenoid |
| 18 | NRPS | - | NRS peptide |
| 19 | PKSI | Saccharomonospora xinjiangensis XJ-54 | Glycosylated polyene macrolide |
| 20 | NRPS | - | Mannopeptimycin-like NRS peptide |
| 21 | PKSI | Amycolatopsis nigrescens CSC17Ta-90 | Hygrocin-like polyketide |
| 22 | Oligosaccharide | Nocardiopsis kunsanensis DSM 44524 | Oligosaccharide |
| 23 | Butyrolactone | - | Butyrolactone |
| 24 | Siderophore | - | Siderophore |
| 25 | PKSII | Microbispora sp. ATCC PTA-5024 | Aromatic polyketide |
Notes: NRS non-ribosomally synthesized. Shaded cells show potentially unique gene clusters. #Presence in other bacteria based on the publically available data as of January 27, 2016