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. 2016 Dec 20;17:542. doi: 10.1186/s12859-016-1402-1

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — BioNet study case. a Analysis of the Jaccard index trend across switching-steps (SS) while rewiring the BioNet reference Interactome and estimation of the lower bound N; b visual inspection of the switching-algorithm Markov chain convergence to verify the suitability of the estimated bound (see Fig. 2 legend for further details); c Interactome module outputted by BioNet while analyzing the DLBCL dataset; d scatter plots of BioNet scores vs. frequency of inclusion in the rewired solutions for all the nodes included in the BioNet module (left plot) and for all the other Interactome nodes contained in the DLBCL dataset (right plot)