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. 2016 Dec 20;52(1):5–11. doi: 10.1093/alcalc/agw082

Fig. 2.

Fig. 2.

Social Approach/Avoidance Test. Rats that had been stressed at the start of the first two alcohol deprivations (D + Stress + Veh) exhibited increased anxiety-like behavior (i.e. decreased social approach) in the social approach/avoidance test during the third (final) deprivation, compared with Control rats (P= 0.05). Prazosin (1.5 mg/kg) treatment before each of the two stresses blocked this stress effect (P< 0.05). Lower dose prazosin (1 mg/kg) treatment before each of the two stresses tended (P = 0.09) to decrease the stress effect. Each bar represents the mean + SEM of 6–7 rats/group.