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. 2016 Nov 15;27(23):3695–3704. doi: 10.1091/mbc.E16-04-0253

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© 2016 Chia et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 2: — PREM of cytoskeleton structure in distal neurite regions. (A) Growth cone and a distal portion of the neurite from a neuron cultured in a normal medium. (a) Boxed region in A enlarged to show actin filament bundle in the filopodium and branched actin network in lamellipodia. (B, C) Actin-rich bulbs and the distal neurite regions from neuron treated with 2.5 μM LatB (B) or 2.5 μM CytoD (C). (b, c) Boxed regions in B and C, respectively, enlarged to show dense branched actin network in the actin bulb. Scale bars, 2 μm (A–C), 200 nm (a–c).