Table 4.
Adverse events that led to treatment discontinuation in 99 patients
| Adverse event | N |
|---|---|
| Recurrent or new-onset uveitis | 38 |
| Neuropsychiatric disorders | 21 |
| Behavioral disorders | 7 |
| Headache | 6 |
| Mood disorders/difficulty concentrating | 4 |
| Tics/unintentional movements | 2 |
| Papilledema | 1 |
| Hypoglossal nerve paralysis | 1 |
| Gastrointestinal disorders | 15 |
| Inflammatory bowel diseases | 10 |
| Persistent hypertransaminasemia | 1 |
| Abdominal pain | 1 |
| Peritonitis anti-DNA positive | 1 |
| Acute pancreatitis | 1 |
| Nausea or vomiting | 1 |
| Infection | 13 |
| Recurrent herpes labialis | 2 |
| Recurrent upper airway infections | 2 |
| Fatal streptococcal sepsis | 1 |
| Tuberculosis | 1 |
| Varicella complicated by porpora fulminans and fasciitis | 1 |
| Osteomyielitis | 1 |
| Cellulitis | 1 |
| Herpetic neuritis | 1 |
| Herpes zoster | 1 |
| CMV hepatitis | 1 |
| Recurrent bronchitis | 1 |
| Mucocutaneous disorders | 10 |
| Urticaria | 4 |
| Urticaria angioedema | 2 |
| Cutaneous vasculitis | 2 |
| Itch | 1 |
| Anal Condylomatosis | 1 |
| Haematological disorders | 5 |
| Leukopenia | 3 |
| Autoimmune thrombocytopenia | 1 |
| Hypocomplementemia | 1 |
| Injection site reactions | 4 |
| Pain at injection site | 3 |
| Malignancy | 2 |
| Thyroid carcinoma | 1 |
| Bladder carcinoma | 1 |
| Others | 6 |
| Persistent cervical lymphadenopathy | 2 |
| Autoimmune thyroiditis | 1 |
| Menometrorrhagia | 1 |
| Abortion | 1 |
| Renal lithiasis | 1 |