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. 2016 Dec 19;9:648. doi: 10.1186/s13071-016-1928-0

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — Pathological changes of livers from challenge infection mice. Liver sections of each group were stained with Masson’s trichrome. Collagen fibers are shown in blue. Panels a–d show mice orally treated with PBS, B.s-CotC, BL21-CsCP and B.s-CotC-CsCP, respectively. Panel (e) provides the statistic of Ishak scores in liver sections from each mouse. *P < 0.05; **P < 0.01. The thick arrows indicate the adult worms of C. sinensis, and the thin arrows indicate collagen deposition in livers. Scale-bars: 200 μm